Person
CONTINI ALESSANDRO
PROFESSORE ASSOCIATO
Fields (8)
Keywords (18)
ANALISI CONFORMAZIONALE DI PEPTIDI E PROTEINE
BIOFISICA
CHIMICA ORGANICA
CONFORMATIONAL ANALYSIS
DINAMICA MOLECOLARE
DRUG DESIGN
INTERAZIONI PROTEINA-PROTEINA, PROTEINA-LIGANDO
MODELLISTICA MOLECOLARE
MOLECULAR DYNAMICS
MOLECULAR MODELLING
NANOMATERIALI
NANOMATERIALS
ORGANIC CHEMISTRY
PEPTIDES
PROGETTAZIONE RAZIONALE DI FARMACI
PROTEIN FOLDING
PROTEIN-PROTEIN INTERACTIONS
VIRTUAL SCREENING
No Results Found
Research overview (4)
Computational design of bioactive compounds (2008 - )
Studies of reaction mechanisms by using quantum-mechanical techniques (2003 - )
folding behavior of peptides containing non-natural amino acids (2011 - )
modulation of biologically relevant protein-protein interaction by chemical compounds (2009 - )
No Results Found
Funded research (8)
2006
6 months
Neural cytoskeleton and Rho GTPases in human models of Intellectual Disability and Microcephaly
PRIN2022 - PRIN bando 2022
Project
Scientific Manager
2023
29 months
2008
Progettazione e sintesi di nuovi inibitori della proteina Racl e loro valutazione farmacologica nell'ambito della terapia cardiovascolare
FIRB-FiR08 - FIRB bando Futuro in Ricerca 2008
Project
Scientific Manager
2010
36 months
Sintesi di amminoacidi non naturali e di peptidomimetici e loro applicazioni
PUR90 - PUR 90%
Project
participant
2009
Sintesi e applicazioni biomediche di peptidomimetici in campo oncologico
PRIN10-11 - PRIN bando 2010-11
Project
participant
2013
36 months
Sviluppo "hit-to-lead" di inibitori delle proteine Rac: da molecola bioattiva a candidato farmaco
RL_PRES - Bandi Presidenza
Project
participant
2010
24 months
sintesi eterocicliche mediante utilizzo di ammidine come sintoni o tramite reazioni di cicloaddizione
PUR20062008 - PUR 2006-2008
Project
participant
2007
No Results Found
Publications (161)
Patents
Awards and honors
Best Poster Award,
conferred by eCheminformatics Conference Chair - Douglas Connect - 2003
No Results Found
Teaching and research activities with third-party institutions
Organization of Drug Discovery Design Methods & Applications; gave lecture 1 on 05/01, 9.30-13.00 and lecture 2 on 06/01, 09.00-13.00; acted as chairman on 07/01, 09.00-18.00 (lectures 5 and 6) at: Ahmedabad University
(05/01/2015 - 09/01/2015)20150105
No Results Found
Doctoral Boards (16)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2025
(cycle: 41 - Year: 2025
2025
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2024
(cycle: 40 - Year: 2024
2024
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2023
(cycle: 39 - Year: 2023
2023
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2022
(cycle: 38 - Year: 2022
2022
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2021
(cycle: 37 - Year: 2021
2021
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2020
(cycle: 36 - Year: 2020
2020
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2019
(cycle: 35 - Year: 2019
2019
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2018
(cycle: 34 - Year: 2018
2018
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2017
(cycle: 33 - Year: 2017
2017
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2016
(cycle: 32 - Year: 2016
2016
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2015
(cycle: 31 - Year: 2015
2015
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2014
(cycle: 30 - Year: 2014
2014
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2013
(cycle: 29 - Year: 2013
2013
)
Università degli Studi di MILANO -
CHIMICA DEL FARMACO-2012
(cycle: 28 - Year: 2012
2012
)
Università degli Studi di MILANO -
CHIMICA DEL FARMACO-2011
(cycle: 27 - Year: 2011
2011
)
Università degli Studi di MILANO -
CHIMICA DEL FARMACO-2010
(cycle: 26 - Year: 2010
2010
)
No Results Found
Tutoring (6)
tutorship -
Dottorandi/e
- OTTAVIANELLI RACHELE
tutorship -
Dottorandi/e
- LANZINI ALESSIA
tutorship -
Dottorandi/e
- AHMED SAEED
tutorship -
Dottorandi/e
- SIMON NICOLAS
tutorship -
Dottorandi/e
- HU XIAO
tutorship -
Dottorandi/e
- MAFFUCCI IRENE
No Results Found
Description
QUALIFICATIONS
March 2018: Associate Professor of Organic Chemistry, Dept. of Pharmaceutical Sciences, Università degli Studi di Milano.
June 2006: assistant professor of organic chemistry, Faculty of Pharmacy, University of Milano.
November 2003: MIUR research fellowship with Prof. P. Trimarco.
May 2003: PhD in Medicinal Chemistry, University of Milano.
July 2002–October 2002: visiting scientist at the laboratory of Prof. Leonardo Scapozza, Department of Applied Biosciences, Pharmaceutical Biochemistry, ETH, Zürich.
July 1999: Laurea in Chemistry and Pharmaceutical Technology, University of Milano (104/110)
TEACHING ACTIVITY
Dr. Contini taught Organic Chemistry at the Faculty of Pharmacy, University of Milano, and at the faculty of Medicine, University of Brescia since a.a. 2006/2007. He also taught “Application of Informatics Techniques to Bioorganic Chemistry” at the Faculty of Pharmacy, University of Milano.
SCIENTIFIC ACTIVITY
The scientific activity is documented by more than 80 articles on international peer reviewed journals, 1 patent application, 1 article on a national journal, 3 book chapter and several communications at national and international congresses ((Total H index 23. H index last 5 years 16. Total citations : 1463. Citation of last 5 years: 886; source Google Scholar)
The research activity concerns organic and computational chemistry, in particular:
•Study of reaction mechanisms by using quantum-mechanical techniques (ab-initio, DFT, MP2).
•Computational and spectroscopic studies of chemical equilibria, optical and spectroscopic properties of organic molecules.
•Studies of Structure Activity Relationships (SAR), 3D-QSAR, virtual screening, and interactions between bioactive molecules and their biological target by mean of docking, molecular mechanics and quantum mechanics.
•Computational studies of the folding mechanisms of biomacromolecules.
•Synthesis of bioactive heterocyclic compounds.
March 2018: Associate Professor of Organic Chemistry, Dept. of Pharmaceutical Sciences, Università degli Studi di Milano.
June 2006: assistant professor of organic chemistry, Faculty of Pharmacy, University of Milano.
November 2003: MIUR research fellowship with Prof. P. Trimarco.
May 2003: PhD in Medicinal Chemistry, University of Milano.
July 2002–October 2002: visiting scientist at the laboratory of Prof. Leonardo Scapozza, Department of Applied Biosciences, Pharmaceutical Biochemistry, ETH, Zürich.
July 1999: Laurea in Chemistry and Pharmaceutical Technology, University of Milano (104/110)
TEACHING ACTIVITY
Dr. Contini taught Organic Chemistry at the Faculty of Pharmacy, University of Milano, and at the faculty of Medicine, University of Brescia since a.a. 2006/2007. He also taught “Application of Informatics Techniques to Bioorganic Chemistry” at the Faculty of Pharmacy, University of Milano.
SCIENTIFIC ACTIVITY
The scientific activity is documented by more than 80 articles on international peer reviewed journals, 1 patent application, 1 article on a national journal, 3 book chapter and several communications at national and international congresses ((Total H index 23. H index last 5 years 16. Total citations : 1463. Citation of last 5 years: 886; source Google Scholar)
The research activity concerns organic and computational chemistry, in particular:
•Study of reaction mechanisms by using quantum-mechanical techniques (ab-initio, DFT, MP2).
•Computational and spectroscopic studies of chemical equilibria, optical and spectroscopic properties of organic molecules.
•Studies of Structure Activity Relationships (SAR), 3D-QSAR, virtual screening, and interactions between bioactive molecules and their biological target by mean of docking, molecular mechanics and quantum mechanics.
•Computational studies of the folding mechanisms of biomacromolecules.
•Synthesis of bioactive heterocyclic compounds.