PALLAVICINI MARCO

A selective antagonist for the neuronal alpha7 nAChR subtype.

NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY.

1998

Abstract

Efficient One-Pot Reductive Aminations of Carbonyl Compounds with Aquivion-Fe as a Recyclable Catalyst and Sodium Borohydride.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY.

2020

Academic Article

Mixed Access

Ten years of fentanyl-like drugs: A technical-analytical review.

ANALYTICAL SCIENCES.

2019

Academic Article

Partially Open Access

1H NMR spectroscopy in the presence of Mosher acid to rapidly determine the enantiomeric composition of amino acid benzyl esters, chirons susceptible to easy racemization.

AMINO ACIDS.

2018

Academic Article

Reserved Access

A simple route to synthesize (E)-3 propyl-4-oxo-2-butenoic acid esters through the Z isomer.

SYNTHETIC COMMUNICATIONS.

2018

Academic Article

Reserved Access

Determination of Methyldibromoglutaronitrile (MDBGN) in Skin Care Products by Gaschromatography-Mass Spectrometry Employing an Enhanced Matrix Removal (EMR) Lipid Clean-Up.

EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY.

2018

Academic Article

Partially Open Access

Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan.

JOURNAL OF MEDICINAL CHEMISTRY.

2018

Academic Article

Reserved Access

Preparation of enantiopure methionine, arginine, tryptophan, and proline benzyl esters in green ethers by Fischer–Speier reaction.

AMINO ACIDS.

2018

Academic Article

Reserved Access

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at alpha4beta2 nicotinic acetylcholine receptor.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.

2017

Academic Article

Reserved Access

One-step preparation of enantiopure L- or D-amino acid benzyl esters avoiding the use of banned solvents.

AMINO ACIDS.

2017

Academic Article

Partially Open Access

Phase Diagrams to Evaluate the Opportunity for Enantiomeric Enrichment of Some Nonracemic Mixtures of Amino Acid Benzyl Esters by Crystallization as p-Toluenesulfonate Salts.

ORGANIC PROCESS RESEARCH & DEVELOPMENT.

2017

Academic Article

Reserved Access

alpha9- and alpha7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line.

BRITISH JOURNAL OF PHARMACOLOGY.

2017

Academic Article

Reserved Access

3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.

2016

Academic Article

A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro".

PHARMACOLOGICAL RESEARCH.

2016

Academic Article

Open Access

Crystallization-based resolution of 1,4-benzodioxane-2-carboxylic acid enantiomers via diastereomeric 1-phenylethylamides.

TETRAHEDRON LETTERS.

2016

Academic Article

Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2016

Academic Article

Reserved Access

Benzodioxane–benzamides as new bacterial cell division inhibitors.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.

2015

Academic Article

Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1,4-benzodioxane, prolinol phenyl ether and prolinol 3-pyridyl ether designed as alpha4beta2-nicotinic acetylcholine receptor agonists.

JOURNAL OF MEDICINAL CHEMISTRY.

2015

Academic Article

Open Access

Enantiomerically Pure Dibenzyl Esters of L‑Aspartic and L‑Glutamic Acid.

ORGANIC PROCESS RESEARCH & DEVELOPMENT.

2015

Academic Article

Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids.

JOURNAL OF CHROMATOGRAPHY. B.

2014

Academic Article

Reserved Access

Farnesyltransferase inhibitors : CAAX mimetics based on different biaryl scaffolds.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2014

Academic Article

From 2-aminomethyl-1,4-benzodioxane enantiomers to unichiral 2-cyano- and 2-carbonyl-substituted benzodioxanes via dichloroamine.

JOURNAL OF ORGANIC CHEMISTRY.

2014

Academic Article

Reserved Access

Simple process for the preparation of cetyltrimethylammonium naproxenate (naprocet).

ORGANIC PROCESS RESEARCH & DEVELOPMENT.

2014

Academic Article

6‑Methoxy-7-benzofuranoxy and 6‑Methoxy-7-indolyloxy Analogues of 2‑[2-(2,6-Dimethoxyphenoxy)ethyl]aminomethyl-1,4- benzodioxane (WB4101) : 1 Discovery of a Potent and Selective α1D Adrenoceptor Antagonist.

JOURNAL OF MEDICINAL CHEMISTRY.

2013

Academic Article

Design, synthesis and binding affinity of acetylcholine carbamoyl analogues.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2013

Academic Article

Diastereomeric 2-aminomethyl-1,4-benzodioxane mandelates : phase diagrams and resolution.

TETRAHEDRON-ASYMMETRY.

2013

Academic Article

Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.

2013

Academic Article

Reserved Access

One-pot racemization process of 1-phenyl-1,2,3,4-tetrahydroisoquinoline : a key intermediate for the antimuscarinic agent solifenacin.

ORGANIC PROCESS RESEARCH & DEVELOPMENT.

2013

Academic Article

Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.

2012

Academic Article

From carnitinamide to 5-aminomethyl-2-oxazolidinones.

TETRAHEDRON-ASYMMETRY.

2012

Academic Article

Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in ‘‘herbal high’’ products on the Italian market.

FORENSIC SCIENCE INTERNATIONAL.

2012

Academic Article

Reserved Access

Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis.

CHIRALITY.

2012

Academic Article

Highly efficient racemisation of a key intermediate of the antibiotic moxifloxacin.

TETRAHEDRON-ASYMMETRY.

2011

Academic Article

Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2011

Academic Article

Unichiral 2-(2′-Pyrrolidinyl)-1,4-benzodioxanes : the 2R,2′S Diastereomer of the N-Methyl-7-hydroxy Analogue Is a Potent α4β2- and α6β2-Nicotinic Acetylcholine Receptor Partial Agonist.

JOURNAL OF MEDICINAL CHEMISTRY.

2011

Academic Article

A highly efficient method for the alpha,beta-dehydrogenation of alpha-amino esters and alpha-amino-beta-diesters.

TETRAHEDRON LETTERS.

2010

Academic Article

An investigation into the influence of counterion on the RS-Propranolol and S-Propranolol skin permeability.

JOURNAL OF PHARMACEUTICAL SCIENCES.

2010

Academic Article

5-(2-Pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes : Synthesis of all the stereoisomers and a4b2 nicotinic affinity.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2009

Academic Article

New Ras CAAX mimetics : design, synthesis, antiproliferative activity, and RAS prenylation inhibition.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2009

Academic Article

Reserved Access

Entrainment resolution of carnitinamide chloride.

TETRAHEDRON-ASYMMETRY.

2008

Academic Article

Modelling of full-length human α4β2 nicotinic receptor by fragmental approach and analysis of its binding modes.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.

2008

Academic Article

Enantiomer systems of carnitinamide inorganic salts: introductory studies to a successful entrainment resolution.

TETRAHEDRON-ASYMMETRY.

2007

Academic Article

Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2007

Academic Article

Resolution of 2-substituted 1,4-benzodioxanes by entrainment.

TETRAHEDRON-ASYMMETRY.

2007

Academic Article

Structural and conformational studies on 5-[1'-methylpyrrolidin-2'-yl]-1,3-oxazolidin-2-one free base and hydrochloride form.

HETEROCYCLES.

2007

Academic Article

Construction of human ghrelin receptor (hGHS-R1a) model using a fragmental prediction approach and validation through docking analysis.

JOURNAL OF MEDICINAL CHEMISTRY.

2006

Academic Article

QSAR study for a novel series of ortho disubstituted phenoxy analogues of a1-adrenoceptor antagonist WB4101.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.

2006

Academic Article

Synthesis and alpha 4 beta 2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2006

Academic Article

WB4101-related compounds: New, subtype-selective alpha(1)-adrenoreceptor antagonists (or inverse agonists?).

JOURNAL OF MEDICINAL CHEMISTRY.

2006

Academic Article

Highly efficient resolutions of 1,4-benzodioxane-2-carboxylic acid with para substituted 1-phenylethylamines.

TETRAHEDRON-ASYMMETRY.

2005

Academic Article

Influence of (S)-1-phenylethylamine para substitution on the resolution of (±)-1,4-benzodioxane-2-carboxylic acid: a crystallographic, theoretical and morphologic approach.

TETRAHEDRON-ASYMMETRY.

2005

Academic Article

QSAR study for a novel series of ortho monosubstituted phenoxy analogues of alpha(1)-adrenoceptor antagonist WB4101.

BIOORGANIC & MEDICINAL CHEMISTRY.

2005

Academic Article

SEARCH FOR SELECTIVE ANTAGONISTS AT α1-ADRENORECEPTOR SUBTYPES: WB-4101 RELATED COMPOUNDS.

SCIENTIA PHARMACEUTICA.

2005

Academic Article

Open Access

Univocal syntheses of 2- and 3-hydroxymethyl-2,3-dihydro[1,4]dioxino[2,3-b]pyridine enantiomers.

TETRAHEDRON-ASYMMETRY.

2005

Academic Article

Resolution of 5-hydroxymethyl-2-oxazolidinone by preferential crystallization[ 1 ] and investigations on the nature of the racemates of some 2-oxazolidinone derivatives.

TETRAHEDRON-ASYMMETRY.

2004

Academic Article

Structure–affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of α1 antagonist WB-4101.

BIOORGANIC & MEDICINAL CHEMISTRY.

2004

Academic Article

Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.

2004

Academic Article

A short entry to enantiopure 2-substituted 1,4-benzodioxanes by efficient resolution methods.

TETRAHEDRON-ASYMMETRY.

2003

Academic Article

Resolution of 1-phenyl-2-( p-tolyl)ethylamine via diastereomeric salt formation.

TETRAHEDRON-ASYMMETRY.

2003

Academic Article

Highly efficient resolutions with isopropylidene glycerol 3-carboxy-2-naphthoate.

TETRAHEDRON-ASYMMETRY.

2002

Academic Article

2-Hydroxymethyl-1,4-dioxane: synthesis, resolution and determination of the absolute configurations of the enantiomers.

ENANTIOMER.

2001

Academic Article

Reciprocal resolutions between 1-phenylethylamine and carboxyesters of isopropylidene glycerol: improvement of the method by replacing mono-phthalate with 3-carboxy-2-naphthoate.

TETRAHEDRON-ASYMMETRY.

2001

Academic Article

Resolution of ortho- and meta-substituted 1-phenylethylamines with isopropylidene glycerol.

TETRAHEDRON-ASYMMETRY.

2001

Academic Article

Synthesis of homochiral 5- and 8-substituted 2-[((2-(2,6-dimethoxyphenoxy)ethyl)amino)methyl]-1,4-benzodioxanes and electrophoretic determination of their enantiomeric excess.

JOURNAL OF ORGANIC CHEMISTRY.

2001

Academic Article

Synthesis, free solution capillary electrophoresis separation and toxicity of seven potential impurities of dobutamine.

ARZNEIMITTEL-FORSCHUNG.

2001

Academic Article

Isopropylidene glycerol hydrogen phthalate as a resolving agent: a study of its diastereomeric salts with (S)- and (R)-1-phenylethylamine.

TETRAHEDRON-ASYMMETRY.

2000

Academic Article

Resolution of beta-unsaturated amines with isopropylidene glycerol hydrogen phthalate.

TETRAHEDRON-ASYMMETRY.

2000

Academic Article

4-oxystilbene compounds are selective ligands for neuronal nicotinic alpha Bungarotoxin receptors.

BRITISH JOURNAL OF PHARMACOLOGY.

1998

Academic Article

Resolution of amines with isopropylidene glycerol hydrogen phthalate.

TETRAHEDRON-ASYMMETRY.

1997

Academic Article

A new convenient synthesis of 1-(4-nitrophenyl)ethylamine from acetophenone.

JOURNAL OF CHEMICAL RESEARCH. SYNOPSES.

1996

Academic Article

Isopropylidene glycerol hydrogen phthalate: a new resolving agent. Application to the resolution of 1-arylethylamines.

TETRAHEDRON-ASYMMETRY.

1996

Academic Article

Relationships between conformational behaviour and binding affinity towards beta1 and beta2 adrenoceptors of some chiral phenoxypropanolamines with bulky N-substituents.

IL FARMACO.

1995

Academic Article

Synthesis of N,N'-dibenzylethylenediamine via palladium-carbon-catalysed reductive alkylation.

JOURNAL OF CHEMICAL RESEARCH. SYNOPSES.

1995

Academic Article

Bakers' yeast reduction of 1-benzyloxy-3-hydroxypropan-2-one.

JOURNAL OF CHEMICAL RESEARCH. SYNOPSES.

1994

Academic Article

Lipase-catalyzed resolution of glycerol 2,3-carbonate.

JOURNAL OF ORGANIC CHEMISTRY.

1994

Academic Article

Molecular properties of the WB4101 enantiomers and of its chiral methyl derivatives for alpha1-adrenoceptor recognition.

IL FARMACO.

1994

Academic Article

New asymmetric synthesis of (−)-esermethole.

TETRAHEDRON-ASYMMETRY.

1994

Academic Article

Synthesis of (-)- and (+)-esermethole via chemical resolution of 1,3-dimethyl-3-(2-aminoethyl)-5-methoxyoxindole.

TETRAHEDRON-ASYMMETRY.

1994

Academic Article

Synthesis of (R)- and (S)-isopropylidene glycerol.

TETRAHEDRON-ASYMMETRY.

1994

Academic Article

Agonistic activity and charge driven intra- and intermolecular interaction potentiality of some PAF derivatives.

IL FARMACO.

1993

Academic Article

Chiral PAF agonists: synthesis, theoretical analysis of their stereoelectronic properties and structure-activity relationships.

IL FARMACO.

1993

Academic Article

Synthesis and ruthenium catalyzed enantioselective hydrogenation of 1,3-dihydroxypropan-2-one 1-ethers.

HELVETICA CHIMICA ACTA.

1993

Academic Article

High-performance liquid chromatography determination of the enantiomeric excess of 1,3-glyceryl diethers obtained by stereoselective catalytic reduction.

JOURNAL OF CHROMATOGRAPHY A.

1992

Academic Article

Ruthenium-catalyzed enantioselective hydrogenation of 1,3-O-disubstituted 1,3-dihydroxypropan-2-ones.

HELVETICA CHIMICA ACTA.

1992

Academic Article

Beta-lactamase inhibiting properties of 6-oxopenicillanic and 7-oxocephalosporanic acid derivatives.

IL FARMACO.

1991

Academic Article

Synthesis of glyceryl ethers in high optical purity via ruthenium catalyzed asymmetric hydrogenation.

TETRAHEDRON LETTERS.

1991

Academic Article

Asymmetric catalytic hydrogenation of alpha-aminoketones by cationic iridium complexes.

JOURNAL OF MOLECULAR CATALYSIS.

1990

Academic Article

Synthesis, binding affinities for alpha-adrenoceptor and eudismic analysis of chiral benzodioxane derivatives and their chiral opened analogues.

IL FARMACO. EDIZIONE SCIENTIFICA.

1988

Academic Article

Microbiological determinations of thiamine, riboflavin, pyridoxine and niacin.

ANNALI DI MICROBIOLOGIA ED ENZIMOLOGIA.

1987

Academic Article

Cardiovascular and pulmonary activity of platelet-activating factor (PAF-acether) and its derivatives.

PHARMACOLOGICAL RESEARCH COMMUNICATIONS.

1986

Academic Article

Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line.

BIOCHEMICAL PHARMACOLOGY.

2015

Conference Poster

Structure Activity Relationship of novel antimicrobial agents, acting as inhibitors of the bacterial cell division protein Ftsz.

2016

Document

Novel inhibitors of the bacterial cell division protein FtsZ: synthesis and antibacterial activity.

2015

Document

Design, synthesis and biological evaluation of peptidomimetic inhibitors of farnesyltransferase.

2012

Document

Heteroaryl carnosine analogues: design, synthesis and carbonyl quenching activity.

2011

Document

Reserved Access

SYNTHESIS AND BINDING AFFINITY OF NEW HIGHLY SELECTIVE alpha4beta2 NICOTINIC LIGANDS.

2011

Document

Reserved Access

SYNTHESIS AND BINDING AFFINITY OF NEW HIGHLY SELECTIVE alpha4beta2 NICOTINIC LIGANDS.

2009

Document

Open Access

HETEROARYLOXY ANALOGUES OF WB4101: SYNTHESIS AND BIOLOGICAL EVALUATION AT ALPHA-1-ADRENOCEPTOR SUBTYPES.

2008

Document

Human skin permeation of racemic and optically active propranolol and propranolol salts.

2007

Document

Synthesis and a4b2 nicotinic affinity of the stereoisomers of 2-(1-methyl-2-pyrrolidinyl)-1,4-benzodioxane and of its nor-methyl derivative.

2007

Document

Reserved Access

ANALOGUES OF ALPHA1-ADRENOCEPTOR ANTAGONIST WB4101: DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION.

2005

Document

ANALOGHI STRUTTURALI DEL WB 4101: PROGETTAZIONE, SINTESI E VALUTAZIONE BIOLOGICA.

2004

Document

DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NON-PEPTIDIC INHIBITORS OF FARNEYLTRANSFRERASE.

2003

Document

The use of the naphthyl probe to scan the alpha-1A/5HT1A receptor binding sites: discovery of novel alpha-1A selective antagonists.

2003

Document

Analisi farmaceutica.

EDRA LSWR.

2014

Edited Book

SUBTYPE-SELECTIVE NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS AND ANTAGONISTS.

2019

Thesis

Open Access

NUOVI LIGANDI DEI RECETTORI NICOTINICI NEURONALI: BENZODIOSSANI E PIRIDODIOSSANI 2-PIRROLIDINIL SOSTITUITI.

2010

Thesis

Reserved Access