PROFESSORE ORDINARIO
Dipartimento di Scienze Farmacologiche e Biomolecolari
Settori (4)
Parole Chiave (3)
ATEROSCLEROSI
HDL
LIPOPROTEINE
Descrizione Linee Ricerca (3)
Caratterizzazione biochimica e clinica del deficit di lecitina:colesterolo aciltransferasi (LCAT) (2002 - )
Difetti genetici di HDL (1998 - )
Farmacologia delle dislipidemie (1988 - )
No Results Found
Ricerca Finanziata (4)
Renal disease in genetic LCAT deficiency: from pathogenesis to therapy. 
FON_NAZ - Bandi Altre Fondazioni
Project
2014
Innovative functional foods based on sweet lupin protein for cardiovascular prevention. 
7PQCP-CSA - 7 Programma Quadro_Collaborative Project/Network/Coordination and Support Action
Project
2011
Innovative functional foods based on sweet lupin protein for cardiovascular prevention. 
7PQCP-CSA - 7 Programma Quadro_Collaborative Project/Network/Coordination and Support Action
Project
2011
No Results Found
Pubblicazioni (222)
Ordina Anno:
Filtra per Pubblicazioni:
Filtra per tipo accesso:
Three new italian cases of LCAT deficiency. 
GIORNALE ITALIANO DELL'ARTERIOSCLEROSI.
2019
Abstract
ABCA1 and HDL3 are Required to Modulate Smooth Muscle Cells Transdifferentiation in a Myocardin-miR143/145-Dependent Process. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY.
2016
Abstract
Reserved Access
High density lipoproteins inhibit oxidative stress-induced prostate cancer cell proliferation. 
THE AMERICAN JOURNAL OF PATHOLOGY.
2016
Abstract
Reserved Access
The biochemical and cardiovascular consequences of LCAT deficiency. 
ATHEROSCLEROSIS.
2008
Abstract
Open Access
Increased ability of sera from LCAT-deficient subjects to promote ABCA1-mediated cholesterol efflux. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY.
2007
Abstract
NORMAL ENDOTHELlAL FUNCTION DESPlTE LOW HDL-CHOLESTEROL LEVELS IN CARRIERS OF THE APOLIPOPROTEIN A-IMitano MUTANT. 
NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES.
2007
Abstract
Open Access
Genotype-phenotype relationship in LCAT deficiencies. 
ATHEROSCLEROSIS SUPPLEMENTS.
2006
Abstract
Lecithin:cholesterol acyltransferase deficiency syndromes. 
ATHEROSCLEROSIS SUPPLEMENTS.
2006
Abstract
Dysfunctional HDL as a therapeutic target for atherosclerosis prevention. 
CURRENT MEDICINAL CHEMISTRY. 
2019
Academic Article
Reserved Access
HDL therapy today: from atherosclerosis, to stent compatibility to heart failure. 
ANNALS OF MEDICINE. 
2019
Academic Article
Mixed Access
Individuals with familial hypercholesterolemia and cardiovascular events have higher circulating Lp(a) levels. 
JOURNAL OF CLINICAL LIPIDOLOGY. 
2019
Academic Article
Open Access
Lipid accumulation impairs lysosomal acid lipase activity in hepatocytes : evidence in NAFLD patients and cell cultures. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 
2019
Academic Article
Reserved Access
Treatment with fibrates is associated with higher LAL activity in dyslipidemic patients. 
PHARMACOLOGICAL RESEARCH. 
2019
Academic Article
Partially Open Access
A proteomic approach to identify novel disease biomarkers in LCAT deficiency. 
JOURNAL OF PROTEOMICS. 
2018
Academic Article
Open Access
Autosomal recessive hypercholesterolemia : long-term cardiovascular outcomes. 
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 
2018
Academic Article
Reserved Access
Effect of soy on metabolic syndrome and cardiovascular risk factors : a randomized controlled trial. 
EUROPEAN JOURNAL OF NUTRITION. 
2018
Academic Article
Partially Open Access
Plasma PCSK9 levels and lipoprotein distribution are preserved in carriers of genetic HDL disorders. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 
2018
Academic Article
Reserved Access
Depletion in LpA-I:A-II particles enhances HDL-mediated endothelial protection in familial LCAT deficiency. 
JOURNAL OF LIPID RESEARCH. 
2017
Academic Article
Reserved Access
Lecithin:cholesterol acyltransferase activation by sulfhydryl-reactive small molecules: Role of cysteine-31. 
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 
2017
Academic Article
Reserved Access
Nutraceutical approaches to metabolic syndrome. 
ANNALS OF MEDICINE. 
2017
Academic Article
Reserved Access
Plasma cholesterol homeostasis, HDL remodeling and function during the acute phase reaction. 
JOURNAL OF LIPID RESEARCH. 
2017
Academic Article
Open Access
High-Density Lipoprotein, Lecithin: Cholesterol Acyltransferase, and Atherosclerosis. 
ENDOCRINOLOGY AND METABOLISM. 
2016
Academic Article
Reserved Access
Lipoprotein X causes renal disease in LCAT deficiency. 
PLOS ONE. 
2016
Academic Article
Open Access
Lomitapide affects HDL composition and function. 
ATHEROSCLEROSIS. 
2016
Academic Article
Partially Open Access
Protective effects of HDL against ischemia/reperfusion injury. 
FRONTIERS IN PHARMACOLOGY. 
2016
Academic Article
Open Access
Role of LCAT in atherosclerosis. 
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 
2016
Academic Article
Reserved Access
Familial LCAT deficiency : from pathology to enzyme replacement therapy. 
CLINICAL LIPIDOLOGY. 
2015
Academic Article
Gender-related lipid and/or lipoprotein responses to statins in subjects in primary and secondary prevention. 
JOURNAL OF CLINICAL LIPIDOLOGY. 
2015
Academic Article
Reserved Access
HDL and atherosclerosis : insights from inherited HDL disorders. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 
2015
Academic Article
Reserved Access
Genetic determinants of HDL metabolism. 
CURRENT MEDICINAL CHEMISTRY. 
2014
Academic Article
HDL and cholesterol handling in the brain. 
CARDIOVASCULAR RESEARCH. 
2014
Academic Article
Reserved Access
Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice. 
PLOS ONE. 
2014
Academic Article
Open Access
A proteomic portrait of atherosclerosis. 
JOURNAL OF PROTEOMICS. 
2013
Academic Article
Reserved Access
Inflammation impairs eNOS activation by HDL in patients with acute coronary syndrome. 
CARDIOVASCULAR RESEARCH. 
2013
Academic Article
Reserved Access
Lipoprotein glomerulopathy associated with a mutation in apolipoprotein e. 
CLINICAL MEDICINE INSIGHTS. CASE REPORTS. 
2013
Academic Article
Open Access
Off-target effects of thrombolytic drugs : apolipoprotein A-I proteolysis by alteplase and tenecteplase. 
BIOCHEMICAL PHARMACOLOGY. 
2013
Academic Article
Reserved Access
A woman with low HDL cholesterol and corneal opacity. 
INTERNAL AND EMERGENCY MEDICINE. 
2012
Academic Article
Characterization of Three Kindreds With Familial Combined Hypolipidemia Caused by Loss-of-Function Mutations of ANGPTL3. 
CIRCULATION, CARDIOVASCULAR GENETICS. 
2012
Academic Article
Reserved Access
Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease. 
ATHEROSCLEROSIS. 
2012
Academic Article
Reserved Access
Lipid and apoprotein composition of HDL in partial or complete CETP deficiency. 
CURRENT VASCULAR PHARMACOLOGY. 
2012
Academic Article
Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations. 
CLINICA CHIMICA ACTA. 
2011
Academic Article
Reserved Access
LCAT deficiency: a nephrological diagnosis. 
GIORNALE ITALIANO DI NEFROLOGIA. 
2011
Academic Article
Macrophage, but not systemic, apolipoprotein E is necessary for macrophage reverse cholesterol transport in vivo. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 
2011
Academic Article
Reserved Access
Native LDL-induced oxidative stress in human proximal tubular cells : multiple players involved. 
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 
2011
Academic Article
Reserved Access
High-density lipoprotein quantity or quality for cardiovascular prevention. 
CURRENT PHARMACEUTICAL DESIGN. 
2010
Academic Article
Lecithin:cholesterol acyltransferase, high-density lipoproteins, and atheroprotection in humans. 
TRENDS IN CARDIOVASCULAR MEDICINE. 
2010
Academic Article
Paradoxical decrease in high density lipoprotein cholesterol with fenofibrate : a quite rare phenomenon indeed. 
CARDIOVASCULAR THERAPEUTICS. 
2010
Academic Article
Reserved Access
Structural and dynamic features of apolipoprotein A-I cysteine mutants, Milano and Paris, in synthetic HDL. 
JOURNAL OF MOLECULAR GRAPHICS & MODELLING. 
2010
Academic Article
Structure and function of the apoA-IV T347S and Q360H common variants. 
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 
2010
Academic Article
Functional LCAT is not required for macrophage cholesterol efflux to human serum. 
ATHEROSCLEROSIS SUPPLEMENTS. 
2009
Academic Article
Novel mutations of CETP gene in Italian subjects with hyperalphalipoproteinemia. 
ATHEROSCLEROSIS SUPPLEMENTS. 
2009
Academic Article
Structural features and dynamics properties of human apolipoprotein A-I in a model of synthetic HDL. 
JOURNAL OF MOLECULAR GRAPHICS & MODELLING. 
2009
Academic Article
ApoA-IMilano from structure to clinical application. 
ANNALS OF MEDICINE. 
2008
Academic Article
Raising HDL cholesterol for cardiovascular disease prevention : is this still feasible?. 
CURRENT CARDIOVASCULAR RISK REPORTS. 
2008
Academic Article
Effects of fenofibrate and simvastatin on HDL-related biomarkers in low-HDL patients. 
ATHEROSCLEROSIS SUPPLEMENTS. 
2007
Academic Article
Molecular characterization of two patients with severe LCAT deficiency. 
NEPHROLOGY DIALYSIS TRANSPLANTATION. 
2007
Academic Article
Role of LCAT in HDL remodeling : investigation of LCAT deficiency states. 
JOURNAL OF LIPID RESEARCH. 
2007
Academic Article
High-density lipoproteins: a therapeutic target for atherosclerotic cardiovascular disease. 
EXPERT OPINION ON THERAPEUTIC TARGETS. 
2006
Academic Article
Japan: are statins still good for everybody?. 
THE LANCET. 
2006
Academic Article
Recombinant apolipoprotein A-IMilano for the treatment of cardiovascular diseases. 
CURRENT ATHEROSCLEROSIS REPORTS. 
2006
Academic Article
High-density lipoproteins attenuate interleukin-6 production in endothelial cells exposed to pro-inflammatory stimuli. 
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 
2005
Academic Article
Synthetic high-density lipoproteins exert cardioprotective effects in myocardial ischemia/reperfusion injury. 
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 
2004
Academic Article
Endothelial protection by high-density lipoproteins: from bench to bedside. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 
2003
Academic Article
Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 
2002
Academic Article
Increased carotid artery intima-media thickness in subjects with primary hypoalphalipoproteinemia. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 
2002
Academic Article
Open Access
The C-terminal domain of apolipoprotein A-I is involved in ABCA1-driven phospholipid and cholesterol efflux. 
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 
2002
Academic Article
Limited proteolysis of a disulfide-linked apoA-I dimer in reconstituted HDL. 
JOURNAL OF LIPID RESEARCH. 
2001
Academic Article
Limited proteolysis of a disulfide-linked apoA-I dimer in reconstituted HDL. 
JOURNAL OF LIPID RESEARCH. 
2001
Academic Article
Limited proteolysis of a disulfide-linked apoA-I dimer in reconstituted HDL.. 
JOURNAL OF LIPID RESEARCH. 
2001
Academic Article
L-carnitine reduces plasma lipoprotein(a) levels in patients with hyper Lp(a). 
NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 
2000
Academic Article
Increased cholesterol efflux potential of sera from ApoA-I-Milano carriers and transgenic mice. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 
1999
Academic Article
Recombinant apolipoproteins for the treatment of vascular diseases. 
ATHEROSCLEROSIS. 
1999
Academic Article
Activation of lecithin cholesterol acyltransferase by a disulfide-linked apolipoprotein A-I dimer. 
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 
1997
Academic Article
Inhibition of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins. 
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 
1997
Academic Article
Human apolipoprotein A-II inhibits the formation of pre-beta high density lipoproteins. 
BIOCHIMICA ET BIOPHYSICA ACTA. L, LIPIDS AND LIPID METABOLISM. 
1996
Academic Article
The molecular structure of apolipoprotein A-II modulates the capacity of HDL to promote cell cholesterol efflux. 
BIOCHIMICA ET BIOPHYSICA ACTA. L, LIPIDS AND LIPID METABOLISM. 
1996
Academic Article
TRIGLYCERIDES ARE MAJOR DETERMINANTS OF CHOLESTEROL ESTERIFICATION/TRANSFER AND HDL REMODELING IN HUMAN PLASMA. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 
1995
Academic Article
DRUG-CONTROL OF REVERSE CHOLESTEROL TRANSPORT. 
PHARMACOLOGY & THERAPEUTICS. 
1994
Academic Article
INCREASED POSTPRANDIAL LIPEMIA IN APO A-I(MILANO) CARRIERS. 
ARTERIOSCLEROSIS AND THROMBOSIS. 
1993
Academic Article
APOLIPOPROTEIN-A-II MODULATES HDL REMODELING IN PLASMA. 
BIOCHIMICA ET BIOPHYSICA ACTA. 
1992
Academic Article
Activity profile of gemfibrozil on the major plasma lipoprotein parameters. 
EUROPEAN JOURNAL OF EPIDEMIOLOGY. 
1992
Academic Article
Tolerability of fibric acids, comparative data and biochemical bases. 
PHARMACOLOGICAL RESEARCH. 
1992
Academic Article
INHIBITION OF ANTIPYRINE METABOLISM BY LOW-DOSE CONTRACEPTIVES WITH GESTODENE AND DESOGESTREL. 
CLINICAL PHARMACOLOGY & THERAPEUTICS. 
1991
Academic Article
OMEGA-3-FATTY-ACIDS SELECTIVELY RAISE HIGH-DENSITY LIPOPROTEIN-2 LEVELS IN HEALTHY-VOLUNTEERS. 
METABOLISM, CLINICAL AND EXPERIMENTAL. 
1991
Academic Article
PREDICTABILITY OF LOW-DENSITY-LIPOPROTEIN LEVELS DURING APHERETIC TREATMENT OF HYPERCHOLESTEROLEMIA. 
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 
1991
Academic Article
ALTERATIONS IN THE HDL SYSTEM AFTER RAPID PLASMA-CHOLESTEROL REDUCTION BY LDL-APHERESIS. 
METABOLISM, CLINICAL AND EXPERIMENTAL. 
1988
Academic Article
Effects of established hypolipidemic drugs on HDL concentration, subclass distribution, and function. 
HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. Springer.
2015
Chapter
Open Access
Structure of HDL : particle subclasses and molecular components. 
HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. Springer.
2015
Chapter
Open Access
Evaluation of the health benefits of soy protein consumption in patients carrying the metabolic syndrome. 
GIORNALE ITALIANO DELL'ARTERIOSCLEROSI.
2015
Conference Poster
Open Access
Vasculoprotective function of HDL from CETP-deficient subjects. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY.
2013
Conference Poster
Normal endothelial function in carriers of the apolipoprotein A-IMilano mutant despite low HDL-cholesterol levels. 
ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY.
2007
Conference Poster
Open Access
Le basi farmacologiche della terapia : il manuale. 
McGraw-Hill.
2008
Edited Book
Farmacoterapia cardiovascolare. 
UTET.
2006
Edited Book
Comitati Editoriali
Direttore di rivista, collana editoriale, enciclopedia - NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2015 - )
No Results Found
Congressi (2)
Program chair (presidente/responsabile del comitato scientifico) - 7th IAS-sponsored Workshop on HDL (2014-01-01 10:32:17.273 - )
Program chair (presidente/responsabile del comitato scientifico) - 80th EAS Satellite Symposium on “High density lipoproteins: from basic science to therapeutic advances” (2012-01-01 10:32:17.265 - )
No Results Found
Collegi Di Dottorato (17)
Ordina Anno:
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE BIOMOLECOLARI, SPERIMENTALI E CLINICHE-2019 (ciclo: 35 - Anno: 2019 )
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE BIOMOLECOLARI, SPERIMENTALI E CLINICHE-2018 (ciclo: 34 - Anno: 2018 )
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE SPERIMENTALI E CLINICHE-2017 (ciclo: 33 - Anno: 2017 )
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE SPERIMENTALI E CLINICHE-2016 (ciclo: 32 - Anno: 2016 )
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE SPERIMENTALI E CLINICHE-2015 (ciclo: 31 - Anno: 2015 )
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE SPERIMENTALI E CLINICHE-2014 (ciclo: 30 - Anno: 2014 )
Università degli Studi di MILANO - SCIENZE FARMACOLOGICHE SPERIMENTALI E CLINICHE-2013 (ciclo: 29 - Anno: 2013 )
Università degli Studi di BARI ALDO MORO - INDIRIZZO DI MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2012 (ciclo: 28 - Anno: 2012 )
Università degli Studi di BARI ALDO MORO - INDIRIZZO DI MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2011 (ciclo: 27 - Anno: 2011 )
Università degli Studi di BARI ALDO MORO - INDIRIZZO DI MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2010 (ciclo: 26 - Anno: 2010 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2009 (ciclo: 25 - Anno: 2009 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2008 (ciclo: 24 - Anno: 2008 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2007 (ciclo: 23 - Anno: 2007 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2006 (ciclo: 22 - Anno: 2006 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2005 (ciclo: 21 - Anno: 2005 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2004 (ciclo: 20 - Anno: 2004 )
Università degli Studi di BARI ALDO MORO - MORFOBIOLOGIA APPLICATA E CITOMETABOLISMO DEI FARMACI-2003 (ciclo: 19 - Anno: 2003 )
No Results Found
Tutoraggio (12)
Ordina Anno:
tutorship - Assegnisti - OSSOLI ALICE FEDERICA (01/03/2020 - 28/02/2021)
tutorship - Assegnisti - PAVANELLO CHIARA (01/03/2020 - 28/02/2022)
tutorship - Assegnisti - PAVANELLO CHIARA (01/07/2019 - 30/06/2020)
tutorship - Dottorandi - STRAZZELLA ARIANNA (01/10/2018 - )
tutorship - Dottorandi - LAURENZI TOMMASO (01/10/2017 - )
tutorship - Assegnisti - SIMONELLI SARA (01/03/2017 - 31/07/2018)
tutorship - Dottorandi - PAVANELLO CHIARA (01/10/2015 - 17/12/2018)
tutorship - Assegnisti - OSSOLI ALICE FEDERICA (01/07/2015 - 30/06/2017)
tutorship - Assegnisti - SIMONELLI SARA (01/02/2015 - 31/01/2017)
tutorship - Assegnisti - SIMONELLI SARA (01/02/2015 - 31/01/2017)
tutorship - Dottorandi - VITALI CECILIA (01/01/2014 - 27/01/2017)
tutorship - Dottorandi - OSSOLI ALICE FEDERICA (01/01/2011 - 16/01/2014)
No Results Found