A structural and conformational study of 8-p-nitrocinnamyl-3-propionyl-3,8-diazabicyclo[3.2.1]-octane, selective agonist of μ-opioid receptors

Articolo
Data di Pubblicazione:
2002
Citazione:
A structural and conformational study of 8-p-nitrocinnamyl-3-propionyl-3,8-diazabicyclo[3.2.1]-octane, selective agonist of μ-opioid receptors / R. Artali, D. Barlocco, G. Bombieri, F. Meneghetti. - In: HETEROCYCLES. - ISSN 0385-5414. - 57:3(2002), pp. 439-447. [10.3987/COM-01-9398]
Abstract:
8-p-Nitrocinnamyl-3-propionyl-3,8-diazabicyclo[3.2.1]octane (2b) and its isomer (1b), having the nitrogen substituents exchanged, have been compared by X-Ray structural analysis. The different orientation of the cinnamyl chain in the two derivatives has been discussed and related to the pharmacological properties.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
R. Artali, D. Barlocco, G. Bombieri, F. Meneghetti
Autori di Ateneo:
MENEGHETTI FIORELLA ( autore )
Link alla scheda completa:
https://air.unimi.it/handle/2434/66100

Aree Di Ricerca

Settori


Settore CHIM/08 - Chimica Farmaceutica