Extra hepatic expression of the acute phase protein alpha 1-acid glycoprotein in normal bovine tissues
Articolo
Data di Pubblicazione:
2009
Citazione:
Extra hepatic expression of the acute phase protein alpha 1-acid glycoprotein in normal bovine tissues / C. Lecchi, G. Avallone, M. Giurovich, P. Roccabianca, F. Ceciliani. - In: THE VETERINARY JOURNAL. - ISSN 1090-0233. - 180:2(2009 May), pp. 256-258. [10.1016/j.tvjl.2007.12.027]
Abstract:
Combined quantitative (real-time) polymerase chain reaction and immunohistochemistry were used to evaluate the expression of the minor acute phase protein alpha 1-acid glycoprotein (AGP, orosomucoid) in bovine extrahepatic tissues. AGP was produced mainly in the salivary glands and spleen, whereas minor expression was detected in all other tissues sampled, including lung, lymph nodes, uterus, ovary, kidney and tongue. The findings were consistent with immunohistochemical results. In view of the immunomodulatory and direct antibacterial activity of AGP, its expression in the salivary glands may signal an involvement in the regulation of the local immunity, even in non-pathological conditions.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Acute phase protein; Alpha 1-acid glycoprotein; Bovine; PCR
Elenco autori:
C. Lecchi, G. Avallone, M. Giurovich, P. Roccabianca, F. Ceciliani
Link alla scheda completa: