A first case description of adrenal gland tumour in a lion (Panthera leo): tomographic and clinico-pathological findings

An 8-year-old male lion with progressive lack of secondary sex characteristics, dysorexia and weight loss was referred to our Institution. The patient was anaesthetized to undergo general clinical evaluation, hematologic, serum biochemical and hormonal profile, FIV/FeLV tests. Total body computed tomography, abdominal ultrasonography and fine-needle aspirates of the liver and left adrenal lesion were performed. Imaging findings showed the presence of a neoplastic lesion on the left adrenal gland and generalized hepatopathy. Blood tests reported an estradiol concentration of 462 ng/dl. To our knowledge, this is the first description of an adrenal mass in a lion associated with secondary feminization.