Epicardial adipocyte hypertrophy : association with M1-polarization and toll-like receptor pathways in coronary artery disease patients

Articolo
Data di Pubblicazione:
2016
Citazione:
Epicardial adipocyte hypertrophy : association with M1-polarization and toll-like receptor pathways in coronary artery disease patients / E. Vianello, E. Dozio, F. Arnaboldi, M.G. Marazzi, C. Martinelli, J. Lamont, L. Tacchini, A. Sigrüner, G. Schmitz, M.M. Corsi Romanelli. - In: NMCD. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. - ISSN 0939-4753. - 26:3(2016 Mar), pp. 246-253. [10.1016/j.numecd.2015.12.005]
Abstract:
In coronary artery disease (CAD) epicardial adipose tissue (EAT) shows an elevated inflammatory infiltrate. Toll-like receptors (TLRs) are important mediators of adipose tissue inflammation and they are able to recognize endogenous products released by damaged cells. Because adipocyte death may be driven by hypertrophy, our aim was to investigate in CAD and non-CAD patients the association between EAT adipocyte size, macrophage infiltration/polarization and TLR-2 and TLR-4 expression.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Coronary artery disease (CAD); Epicardial adipose tissue (EAT); Macrophages infiltration; Toll-like receptors (TLRs)
Elenco autori:
E. Vianello, E. Dozio, F. Arnaboldi, M.G. Marazzi, C. Martinelli, J. Lamont, L. Tacchini, A. Sigrüner, G. Schmitz, M.M. Corsi Romanelli
Autori di Ateneo:
ARNABOLDI FRANCESCA ( autore )
CORSI ROMANELLI MASSIMILIANO MARCO ( autore )
DOZIO ELENA ( autore )
MARTINELLI CARLA ( autore )
TACCHINI LORENZA ( autore )
VIANELLO ELENA ( autore )
Link alla scheda completa:
https://air.unimi.it/handle/2434/363732