Phenyl Formate as a CO Surrogate for the Reductive Cyclization of Organic Nitro Compounds to Yield Different N-Heterocycles: No Need for Autoclaves and Pressurized Carbon Monoxide †
Articolo
Data di Pubblicazione:
2023
Citazione:
Phenyl Formate as a CO Surrogate for the Reductive Cyclization of Organic Nitro Compounds to Yield Different N-Heterocycles: No Need for Autoclaves and Pressurized Carbon Monoxide † / F. Ragaini, F. Ferretti, M.A. Abdellatif. - In: CATALYSTS. - ISSN 2073-4344. - 13:2(2023 Jan 18), pp. 224.1-224.10. [10.3390/catal13020224]
Abstract:
The reductive cyclization of different organic nitro compounds by carbon monoxide, catalyzed by transition metal complexes, is a very efficient and clean strategy for the synthesis of many N-heterocycles. However, its use requires the use of autoclaves and pressurized CO lines. In this perspective, the authors will present the results obtained in their laboratories on the use of phenyl formate as a convenient CO surrogate, able to liberate carbon monoxide under the reaction conditions and allowing the use of a cheap glass pressure tube as a reaction vessel. In most cases, yields were better than those previously reported by the use of pressurized CO, proving that the use of CO surrogates can be a viable alternative to the gaseous reagent.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
carbazoles; carbon monoxide; carbonylation reactions; co-surrogate; homogeneous catalysis; indoles; nitroalkenes; nitroarenes; oxazines; palladium
Elenco autori:
F. Ragaini, F. Ferretti, M.A. Abdellatif
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