Immunosuppressive therapy in pancreas and islet transplant : Need for simultaneous assessment of insulin sensitivity and secretion
Articolo
Data di Pubblicazione:
2013
Citazione:
Immunosuppressive therapy in pancreas and islet transplant : Need for simultaneous assessment of insulin sensitivity and secretion / S. Benedini, A. Caumo, I. Terruzzi, L. Luzi. - In: JOURNAL OF DIABETES MELLITUS. - ISSN 2160-5831. - 3:3(2013 Aug), pp. 156-160. [10.4236/jdm.2013.33024]
Abstract:
Diabetes mellitus is a metabolic disease possi- ble to treat via pancreas/islet transplantation but most immunosuppressive drugs are diabeto- genic. In this letter, we review current up to date methods to assess insulin action and secretion (using the surrogate indexes) suggesting their use in large studies in populations of pancreas/ islets transplanted patients.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Pancreas-Islets Transplantation ; Insulin Sensitivity ; Insulin Secretion ; HOMA (The Homeostasis Model Assessment) ; QUICKI (The Quantitative Insulin-Sensitivity Check Index) ; Hyperinsulinemic Clamp
Elenco autori:
S. Benedini, A. Caumo, I. Terruzzi, L. Luzi
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