Asymmetric cyclopropanation of olefins catalysed by Cu(I) complexes of chiral pyridine-containing macrocyclic ligands (Pc-L*)
Articolo
Data di Pubblicazione:
2013
Citazione:
Asymmetric cyclopropanation of olefins catalysed by Cu(I) complexes of chiral pyridine-containing macrocyclic ligands (Pc-L*) / B. Castano, S. Guidone, E. Gallo, F. Ragaini, N. Casati, P. Macchi, M. Sisti, A. Caselli. - In: DALTON TRANSACTIONS. - ISSN 1477-9226. - 42:7(2013 Feb 21), pp. 2451-2462.
Abstract:
The synthesis and characterisation of copper(I) complexes of chiral pyridine-containing macrocyclic ligands (Pc-L*) and their use as catalysts in asymmetric cyclopropanation reactions are reported. All ligands and metal complexes were fully characterised, including crystal structures of some species determined by X-ray diffraction on single crystals. This allowed characterising the very different conformations of the macrocycles which could be induced by different substituents or by metal complexation. The strategy adopted for the ligand synthesis is very flexible allowing several structural modifications. A small library of macrocyclic ligands possessing the same donor properties but with either C1 or C2 symmetry was synthesized. Cyclopropane products with both aromatic and aliphatic olefins were obtained in good yields and enantiomeric excesses up to 99%.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Copper complexes ; Cu complexes ; Cyclopropanation ; Cyclopropanation reaction ; Enantiomeric excess ; Macro-cyclic ligands ; Macrocycles ; Metal complexation ; Structural modifications
Elenco autori:
B. Castano, S. Guidone, E. Gallo, F. Ragaini, N. Casati, P. Macchi, M. Sisti, A. Caselli
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