Proteomic study of antibiotic resistance in Escherichia coli strains

Enteropathogen Escherichia coli infection is the most common type of colibacillosis of young animals (primarily pigs and calves), and it is cause of diarrhoea among travellers and children in the developing world. The main virulence attributes of pathogens Escherichia coli are adhesins and enterotoxins, which are mostly regulated on large plasmids. In the current study, comparative proteomics was applied to identify changes in proteins responsible for antibiotic resistance in different in vivo isolates Escherichia coli. In particular it has been studied strains with same virulence factors, but a completely different antibiotic profile, obtained from different organs of the same animal