Effect of acetyl-L-carnitine in the treatment of painful peripheral neuropathies in HIV+ patients
Articolo
Data di Pubblicazione:
1997
Citazione:
Effect of acetyl-L-carnitine in the treatment of painful peripheral neuropathies in HIV+ patients / E. Scarpini, G. Sacilotto, P. Baron, M. Cusini, G. Scarlato. - In: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. - ISSN 1085-9489. - 2:3(1997), pp. 250-252.
Abstract:
We studied the effects of acetyl-L-carnitine on pain in 16 HIV+ patients affected by painful distal symmetrical neuropathy. Patients were treated with 0.5-1 gr per day of acetyl-L-carnitine either i.m. or i.v. for 3 weeks. Pain intensity was measured before and after the treatment by the Huskisson's analogic scale. Ten patients (62.5%) reported an improvement of symptoms, five patients (31.25%) were unchanged, one patient worsened. The results of this open study show that acetyl-L-carnitine can have a role in the treatment of pain in distal symmetrical polyneuropathy related to HIV infection. However, further double-blind, placebo-controlled studies are needed to confirm these preliminary results.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Acetyl-L-carnitine; AIDS; Chronic pain; HIV+ neuropathy; Painful distal symmetrical polyneuropathy; Peripheral neuropathy; Therapy of peripheral neuropathies
Elenco autori:
E. Scarpini, G. Sacilotto, P. Baron, M. Cusini, G. Scarlato
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