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Hypokalemic rhabdomyolysis without watery diarrhea : an unexpected presentation of a pancreatic neuro-endocrine tumor

Articolo
Data di Pubblicazione:
2006
Citazione:
Hypokalemic rhabdomyolysis without watery diarrhea : an unexpected presentation of a pancreatic neuro-endocrine tumor / V. Rossi, S. Saibeni, L. Sinigaglia, M. Peracchi, A. Parafioriti, M. Vecchi. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 101:3(2006), pp. 669-672. [10.1111/j.1572-0241.2006.00392.x]
Abstract:
Pancreatic polypeptide (PP) islet cell tumors are usually not assocd. with a distinct clin. syndrome, although some reports suggest that they can cause a watery diarrhea syndrome similar to vasoactive intestinal polypeptide (VIP) cell tumors. We report the case of a young woman with an unusual presentation of a pancreatic neuroendocrine tumor mainly secreting PP. The patient developed a reversible hypokalemic rhabdomyolysis very likely secondary to the presence of the tumor. The myopathy resolved following the restoration of normokaliemia using potassium supplementation and a partial laparoscopic pancreatectomy. Isolated cases of hypokalemic rhabdomyolysis induced by intestinal diseases have been described in literature but these did not include gastroenteropancreatic neoplasms. We suggest that pancreatic neuroendocrine tumors should be added to the list of intestinal diseases capable of producing hypokalemic myopathy. [on SciFinder (R)]
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Chromogranins Role : ADV (Adverse effect, including toxicity), BSU (Biological study, unclassified), BIOL (Biological study) (A ; life-threatening hypokalemic rhabdomyolysis without watery diarrhea was seen in patient with pancreatic neuroendocrine neoplasm predominantly secreting pancreatic polypeptide) ; Diarrhea ; Human ; Pancreas (life-threatening hypokalemic rhabdomyolysis without watery diarrhea was seen in patient with pancreatic neuroendocrine neoplasm predominantly secreting pancreatic polypeptide) ; Antibodies and Immunoglobulins Role : BUU (Biological use, unclassified), BIOL (Biological study), USES (Uses) (monoclonal, indium complexes, labeled with indium-111 ; life-threatening hypokalemic rhabdomyolysis without watery diarrhea was seen in patient with pancreatic neuroendocrine neoplasm predominantly secreting pancreatic polypeptide) ; Muscle (rhabdomyolysis ; life-threatening hypokalemic rhabdomyolysis without watery diarrhea was seen in patient with pancreatic neuroendocrine neoplasm predominantly secreting pancreatic polypeptide)
Elenco autori:
V. Rossi, S. Saibeni, L. Sinigaglia, M. Peracchi, A. Parafioriti, M. Vecchi
Link alla scheda completa:
https://air.unimi.it/handle/2434/29564
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Settore MED/12 - Gastroenterologia
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