Pharmaceutical formulations of nimesulide

Nimesulide is widely used to accomplish both topical and systemic therapeutic goals. Topical multi-dose semi-solid formulations for cutaneous application as well as single-dose prepns. for bioadhesion onto the buccal mucosal were proposed for local and regional treatments. On the other hand, many different oral, rectal and injectable dosage forms were developed to achieve a systemic therapeutic effect through the administration of nimesulide. Some of the nimesulide formulations developed for topical and systemic administration are discussed.