Platelet cryopreservation using second-messenger effector and low-dose (2%) dimethyl sulfoxide. In vitro evaluation of post-thawing platelet activity with the platelet function analyzer

Second-messenger effectors (ThromboSol(R)), together with low-dose dimethyl sulfoxide (DMSO) (2%), are described as a new cryopreservation solution. The solution allows high yield recovery of cryopreserved platelets with a residual platelet function equal or superior to that of 6% DMSO-cryopreserved platelets. The hemostatic function of cryopreserved platelets was measured by PFA-100(TM).