Palladium-catalyzed alkynylation

A brief overview of the scope of the four major protocols with respect to the electrophilic cross-coupling partners is presented in somewhat irrespective of relative merit and demerits among these protocols. Thus, some noteworthy recent advances in which more critical comparisons among the four protocols mentioned will made are discussed. In addition, some recent methodological developments with emphasis on searches for superior phosphine and other ligands as well as one mechanistic aspects of the Pd-catalyzed alkynylation are discussed as well.