First round of a focused library of cholera toxin inhibitors

Articolo

Data di Pubblicazione:

2007

Citazione:

First round of a focused library of cholera toxin inhibitors / Č. Podlipnik, I. Velter, B. La Ferla, G. Marcou, L. Belvisi, F. Nicotra, A. Bernardi. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - 342:12/13(2007), pp. 1651-1660.

Abstract:

C-Galactosides have been used as scaffolds to design a library of non-hydrolysable inhibitors of cholera toxin (CT). Test elements from the library were synthesized and found to inhibit CT binding to an asialofetuin-coated SPR chip with micromolar affinity. Preliminary results are reported.

Tipologia IRIS:

01 - Articolo su periodico

Keywords:

Carbohydrate mimics ; Cholera toxin ; Glycomimetics ; C-Glycosides ; GM1 ganglioside

Elenco autori:

Č. Podlipnik, I. Velter, B. La Ferla, G. Marcou, L. Belvisi, F. Nicotra, A. Bernardi

Autori di Ateneo:

BELVISI LAURA ( autore )

BERNARDI ANNA ( autore )

Link alla scheda completa:

https://air.unimi.it/handle/2434/38449

Aree Di Ricerca

Settori

SSD old (valido fino al 24/06/2024)

Settore CHIM/06 - Chimica Organica

First round of a focused library of cholera toxin inhibitors

Č. Podlipnik, I. Velter, B. La Ferla, G. Marcou, L. Belvisi, F. Nicotra, A. Bernardi

Aree Di Ricerca

Settori