Factor X Shanghai : a mutation disrupting translocation to the endoplasmic reticulum

autosomal recessive inheritance; bleeding disorder; blood clotting factor 10 deficiency; blood clotting; disease severity; endoplasmic reticulum; ex vivo study; gene expression; gene mutation; gene translocation; genetic trait; heavy chain; homozygosity; human; missense mutation; note; protein domain; enzyme precursor; mutant protein