Microstructural and mechanical characteristics of PHEMA-based nanofibre-reinforced hydrogel under compression
Articolo
Data di Pubblicazione:
2015
Citazione:
Microstructural and mechanical characteristics of PHEMA-based nanofibre-reinforced hydrogel under compression / W. Zhao, Z. Shi, X. Chen, G. Yang, C. Lenardi, C. Liu. - In: COMPOSITES. PART B, ENGINEERING. - ISSN 1359-8368. - 76(2015), pp. 292-299. [10.1016/j.compositesb.2015.02.033]
Abstract:
Natural network-structured hydrogels (e.g. bacterial cellulose (BC)) can be synthesised with specific artificial hydrogels (e.g. poly(2-hydroxyethyl methacrylate) (PHEMA)) to form a tougher and stronger nanofibre-reinforced composite hydrogel, which possesses micro-and nano-porous structure. These synthetic hydrogels exhibit a number of advantages for biomedical applications, such as good biocompatibility and better permeability for molecules to pass through. In this paper, the mechanical properties of this nanofibre-reinforced hydrogel containing BC and PHEMA have been characterised in terms of their tangent modulus and fracture stress/strain by uniaxial compressive testing. Numerical simulations based on Mooney-Rivlin hyperelastic theory are also conducted to understand the internal stress distribution and possible failure of the nanofibre-reinforced hydrogel under compression. By comparing the mechanical characteristics of BC, PHEMA, and PHEMA-based nanofibre reinforced hydrogel (BC-PHEMA) under the compression, it is possible to develop a suitable scaffold for tissue engineering on the basis of fundamental understanding of mechanical and fracture behaviours of nanofibre-reinforced hydrogels.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
A. 3-Dimensional reinforcement; B. Fracture; B. Mechanical properties; C. Computational modelling; C. Finite element analysis (FEA); Ceramics and Composites; Mechanics of Materials; Industrial and Manufacturing Engineering; Mechanical Engineering
Elenco autori:
W. Zhao, Z. Shi, X. Chen, G. Yang, C. Lenardi, C. Liu
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