Data di Pubblicazione:
2015
Citazione:
Long noncoding RNAs and microRNAs in cardiovascular pathophysiology / T. Thum, G. Condorelli. - In: CIRCULATION RESEARCH. - ISSN 0009-7330. - 116:4(2015 Feb), pp. 751-762. [10.1161/CIRCRESAHA.116.303549]
Abstract:
RNAs not encoding proteins have gained prominence over the last couple of decades as fundamental regulators of cellular function. Not surprisingly, their dysregulation is increasingly being linked to pathology. Here, we review recent reports investigating the pathophysiological relevance of this species of RNA for the cardiovascular system, concentrating mainly on recent findings on long noncoding RNAs and microRNAs in cardiac hypertrophy and failure.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Cardiac hypertrophy; Cardiac remodelling; Heart failure; lncRNAs; MicroRNAs; Myocardial infarction; Animals; Cardiovascular Diseases; Cardiovascular System; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; MicroRNAs; Phenotype; RNA, Long Noncoding; Signal Transduction; Physiology; Cardiology and Cardiovascular Medicine; Medicine (all)
Elenco autori:
T. Thum, G. Condorelli
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