Multicomponent access to novel dihydroimidazo[1′,5′:1,2]pyrido[3,4-b]indol-2-ium salts and indoles by means of Ugi/Bischler–Napieralski/heterocyclization two step strategy
Articolo
Data di Pubblicazione:
2014
Citazione:
Multicomponent access to novel dihydroimidazo[1′,5′:1,2]pyrido[3,4-b]indol-2-ium salts and indoles by means of Ugi/Bischler–Napieralski/heterocyclization two step strategy / A. Silvani, G. Lesma, S. Crippa, V. Vece. - In: TETRAHEDRON. - ISSN 0040-4020. - 70:26(2014), pp. 3994-4001. [10.1016/j.tet.2014.04.081]
Abstract:
A simple, efficient and general two step procedure, through a sequential Ugi reaction followed by a BischlereNapieralski/
heterocyclization tandem closure, to give novel 6,11-dihydro-5H-imidazo[10,50:1,2]
pyrido[3,4-b]indol-2-ium salt derivatives, is described. By changing the amine and the acid components
with ammonium formate, the same procedure affords 6,11-dihydro-5H-imidazo[10,50:1,2]pyrido[3,4-b]
indole derivatives.
heterocyclization tandem closure, to give novel 6,11-dihydro-5H-imidazo[10,50:1,2]
pyrido[3,4-b]indol-2-ium salt derivatives, is described. By changing the amine and the acid components
with ammonium formate, the same procedure affords 6,11-dihydro-5H-imidazo[10,50:1,2]pyrido[3,4-b]
indole derivatives.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Carboline; Imidazolium salt; Isonitrile; Multicomponent reaction; Ugi reaction
Elenco autori:
A. Silvani, G. Lesma, S. Crippa, V. Vece
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