Acquired echinocandin resistance in a Candida krusei blood isolate confirmed by mutations in the fks1 gene

Academic Article
Publication Date:
2014
Citation:
Acquired echinocandin resistance in a Candida krusei blood isolate confirmed by mutations in the fks1 gene / A.C.M. Prigitano, M.C. Esposto, M. Cogliati, L. Pitzurra, C. Santamaria, A.M. Tortorano. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - 37:2(2014 Apr), pp. 237-240.
abstract:
We describe a case of bloodstream infection caused by a Candida krusei strain that developed echinocandin resistance during caspofungin therapy. Three mutations were found in the HS1 region of the fks1 gene, two of them have never been reported either in C. krusei nor in C. albicans.
IRIS type:
01 - Articolo su periodico
Keywords:
Candida krusei; Echinocandin resistance; Gene mutation
List of contributors:
A.C.M. Prigitano, M.C. Esposto, M. Cogliati, L. Pitzurra, C. Santamaria, A.M. Tortorano
Authors of the University:
PRIGITANO ANNA CRISTINA MARIA ( author )
Link to information sheet:
https://air.unimi.it/handle/2434/236052

Research Areas

Concepts


Settore MED/42 - Igiene Generale e Applicata