Dna2 offers support for stalled forks

Articolo
Data di Pubblicazione:
2012
Citazione:
Dna2 offers support for stalled forks / M.S. Lai, M. Foiani. - In: CELL. - ISSN 0092-8674. - 149:6(2012 Jun 08), pp. 1181-1183.
Abstract:
The ATR and ATM checkpoint kinases preserve the integrity of replicating chromosomes by preventing the reversal of stalled and terminal replication forks. Hu et al. now show that the ATR pathway targets the Dna2 nuclease to process stalled forks and counteract fork reversal.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
REPLICATION FORKS ; GENOME STABILITY ; REVERSAL
Elenco autori:
M.S. Lai, M. Foiani
Autori di Ateneo:
FOIANI MARCO ( autore )
Link alla scheda completa:
https://air.unimi.it/handle/2434/233297

Aree Di Ricerca

Settori


Settore BIO/11 - Biologia Molecolare