Sequential addition and cyclization processes of α,β-Ynones and α,β-Ynoates containing proximate nucleophiles

This review examines sequential processes involving α,β-ynones and α,β-ynoates containing proximate nucleophiles as useful building blocks for the synthesis of heterocyclic derivatives through conjugate-addition-type, pericyclic and transition-metalcatalyzed transfer hydrogenation, hydroarylation, hydrovinylation, or hydroalkynylation reactions followed by heterocyclization.