Sustained lung inflation to manage preterm infants (25–29 weeks' gestation) in the delivery room : the Italian SLI study

There is not a conclusive role of Sustained Lung Inflation (SLI) in the management of preterm infants at risk for RDS in the delivery room. This strategy would permit lung recruitment immediately after birth through delivery of brief peak pressure to the infant airways via a nasopharyngeal tube or mask allowing preterm infants to achieve FRC and reduce need of mechanical ventilation. We planned in Italy a randomized controlled trial (RCT) to confirm or refute these findings.