Data di Pubblicazione:
2012
Citazione:
Synthesis of two unnatural oxygenated aaptaminoids / G. Abbiati, A. Doda, M. Dell'Acqua, V. Pirovano, D. Facoetti, S. Rizzato, E. Rossi. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 77:22(2012 Nov 16), pp. 10461-10467.
Abstract:
Two unprecedented oxygenated aaptaminoids
have been synthesized starting from cheap and easily available
2,3-dihydroxybenzoic acid with the satisfactory overall yields of
31% and 34%. The key step of the procedure is the divergent
thermic 5-exodig vs base-promoted 6-endodig cyclization of a 5-
alkynylquinolinone derivative.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
aaptamine; aaptaminoids; cyclization; total synthesis
Elenco autori:
G. Abbiati, A. Doda, M. Dell'Acqua, V. Pirovano, D. Facoetti, S. Rizzato, E. Rossi
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