Interactions between caveolin-1 and sphingolipids, and their functional relevance
Contributo in Atti di convegno
Data di Pubblicazione:
2012
Citazione:
Interactions between caveolin-1 and sphingolipids, and their functional relevance / S. Sonnino, S. Prioni, V. Chigorno, A. Prinetti (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY). - In: Biochemical roles of eukaryotic cell surface macromolecules : 2011 ISCSM proceedings / [a cura di] P.R. Sudhakaran, A. Surolia. - New York : Springer, 2012. - ISBN 9781461433804. - pp. 97-115 (( convegno International symposium on the biochemical role of eukaryotic cell surface macromolecules (ISCSM) tenutosi a Trivandrum, India nel 2011 [10.1007/978-1-4614-3381-1_8].
Abstract:
Caveolin-1 (CAV-1) is the pivot of a very complex network of interactions that are able to regulate the composition of CAV-1-signaling complexes, the lateral organization of CAV-1 with other molecules within the plasma membrane and the equilibrium between different cellular pools of CAV-1, switching on and off CAV-1- mediated biological events depending on the specific context. The role of sphingolipids in this scenario is very important: sphingolipids can affect CAV-1-mediated biological events due to their multifaceted liaison with caveolin-1. In this review, we discuss the role of CAV-1 as a molecular organizer and in particular we focus on the influence of sphingolipids on this role.
Tipologia IRIS:
03 - Contributo in volume
Elenco autori:
S. Sonnino, S. Prioni, V. Chigorno, A. Prinetti
Link alla scheda completa:
Titolo del libro:
Biochemical roles of eukaryotic cell surface macromolecules : 2011 ISCSM proceedings