Phenotyping of type II and IV hyperlipoproteinemias by a simple, quantitative agarose gel lipoprotein electrophoresis

From the statistical analysis of the densitometric percentage counts derived from 97 lipoprotein electrophoreses from patients with Type II or Type IV hyperlipoproteinemia, we developed a simple sequential screening approach. The method is highly accurate in assigning patients to their proper diagnostic classification. Also, the method is nonparametric, i.e., distribution-free, and considers one variable at a time for discrimination. This method, apart from sampling errors, does not give misclassified patients, but may give some undecided cases.