Cyclotron production, Radiochemical separation and quality control of very high specific activity radiotracers for toxicological studies

The use of High Specific Activity Radiotracers, obtained by either proton or alpha cyclotron irradiation, followed by selective radiochemical separation from the irradiated target in No Carrier Added form, is a powerful analytical tool. The main applications of this method are related to toxicological, environmental and industrial studies, other than to nuclear medicine radiodiagnostic. Some relevant original data on the optimised cyclotron production of technetium and platinum γ-emitting radionuclides are presented.