PATCH FOR LOCAL AND TRANSDERMAL ADMINISTRATION OF ACTIVE INGREDIENTS CONTAINING ANIONIC OR ELECTRON-ATTRACTING GROUPS

A patch for local and transdermal administration of active ingredients containing anionic or electron attracting groups comprising: a) a prevalently aqueous polymeric matrix containing said active ingredient, whose polymer is selected from the group consisting of: a-1) an anionic copolymer of methacrylic acid with a methacrylate ester with a C1-C10 linear or branched alcohol, a-2) a cationic copolymer of methacrylic acid with a C1-C10 linear or branched alcohol containing a tertiary aminic group, and a neutral methacrylate ester with a C1-C10 linear or branched alcohol, said polymeric matrix further comprising: a3) high molecular weight polyvinylpyrrolidone, a4) a plasticizer, b) a backing layer which the matrix is adhered to, c) a protective film removable at the moment placed on said polymeric matrix (a). This patch allows to release effective concentration of said active ingredients and may be removed without leaving residue on the protective film or on the skin.