Plasma interleukin-1 beta concentrations in panic disorder

Plasma interleukin-1β (IL-1β) concentrations were measured in 10 outpatients with panic disorder before and on days 30 and 32 of treatment with alprazolam (2-2.5 mg/day). IL-1β concentrations were found to be significantly higher in patients than in control subjects both before and during therapy. Thus, IL-1β levels may be a marker of panic disorder that is not related to the current level of symptomatology.