Data di Pubblicazione:
2003
Citazione:
Resistance proof, folding-inhibitor drugs / R. A. Broglia, G. Tiana , R. Berera. - In: THE JOURNAL OF CHEMICAL PHYSICS. - ISSN 0021-9606. - 118:10(2003), pp. 4754-4758.
Abstract:
An overview is given of the design of drugs which interfere with the folding mechanism of the target protein, destabilizing it and making it prone to proteolisis. It is shown that these drugs are efficient, specific, and do not suffer from the upraise of resistance.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
R. A. Broglia, G. Tiana , R. Berera
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