The preparation of long chain-hydroxyacyl thiol esters: 3-hydroxyoctadecanoyl-CoA

Attempts to prepare 3-hydroxyoctadecanoyl-CoA by classical methods in fair yields failed, but it was synthesized in 30-35% yields by transesterification of 4-nitrophenyl 3-hydroxyoctadecanoate with the lithium salt of coenzyme A.