Organic synthesis planning: a new algorithm for strategic bond perception

A new algorithm which generates breaking suggestion for Organic Synthesis Planning (OSP) is described. A new strategical approach to organic synthesis design has been used. New definition for structural complexity weight, atom complexity distance, molecular centre, Minimal Sets of Strategic Bonds are presented. The need for separate program sections for the strategic part and the transformation model is addressed. Some results are given and comments made to illustrate the algorithm performance.