Vitamin nutrition in patients with chronic renal failure and dietary manipulation

(1) Vitamin abnormalities in patients with CRF are frequent and appear early even with mild renal failure; (2) early supplementation with water-soluble vitamins should be given to patients on low-protein diets--the amount of the supplementation, however, remains to be determined; (3) fat-soluble vitamin supplements (A and E) should be avoided and their dietary intake limited, and (4) it is obvious that vitamin nutrition in patients with CRF requires further investigation.