[Episodes of amyloidosis in young hens after repeated use of antibacterial oil emulsion vaccines]

Outbreaks of systemic amyloidosis with moderate to high mortality in two young layer flocks are described. In both the cases anamnesis reported repeated vaccinations with oil-emulsified bacterins. Grossly, the liver was enlarged, friable and pale. Hepatic rupture and haemorrhages were frequently seen. Moreover heavy granulomatous reactions at the inoculation site was observed. Histologically amyloid deposition was present in the liver and the spleen of the animals from both of the flocks. Histochemical reactions confirm that it is type AA amyloidosis.