Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases
Articolo
Data di Pubblicazione:
1995
Citazione:
Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases / G. Taraboletti, A. Garofalo, D. Belotti, T. Drudis, P. Borsotti, E. Scanziani, P. D. Brown, R. Giavazzi. - In: JOURNAL OF THE NATIONAL CANCER INSTITUTE. - ISSN 0027-8874. - 87:4(1995 Feb 15), pp. 293-8-298.
Abstract:
The importance of matrix metalloproteinases in angiogenesis, tumor growth, and metastasis is well known. However, little is known about the role of matrix metalloproteinases in the formation of hemangiomas and about the possible therapeutic use of matrix metalloproteinase inhibitors in aggressive vascular tumors.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Neoplasm Invasiveness; Animals; Dose-Response Relationship, Drug; Hemangioendothelioma; Mice; Thiophenes; Neovascularization, Pathologic; Time Factors; Phenylalanine; Metalloendopeptidases; Female
Elenco autori:
G. Taraboletti, A. Garofalo, D. Belotti, T. Drudis, P. Borsotti, E. Scanziani, P. D. Brown, R. Giavazzi
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