Determination of primary active constituents in cannabis preparations by high-resolution gas chromatography/flame ionization detection and high-performance liquid chromatography/UV detection

For a complete quant. anal. of primary active constituents in Cannabis prepns. Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN), the authors have compared two different chromatog. techniques, high-resoln. gas chromatog. (HRGC)/flame ionization detection (FID) and high-performance liq. chromatog. (HPLC)/UV. The two different methods have been validated using crude drug (hashish) with Me oleate and tetraphenylethylene as internal std. for HRGC/FID and HPLC/UV, resp.