Adenylate deaminase (5 '-adenylic acid deaminase, AMPDA)-catalyzed deamination of 5 '-deoxy-5-substituted and 5 '-protected adenosines: A comparison with the catalytic activity of adenosine deaminase (ADA)
Articolo
Data di Pubblicazione:
2003
Citazione:
Adenylate deaminase (5 '-adenylic acid deaminase, AMPDA)-catalyzed deamination of 5 '-deoxy-5-substituted and 5 '-protected adenosines: A comparison with the catalytic activity of adenosine deaminase (ADA) / P. Ciuffreda, A. Loseto,L. Alessandrini, G. Terraneo, E. Santaniello. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2003:24(2003), pp. 4748-4751.
Abstract:
The enzyme adenylate deaminase (AMPDA) is able to catalyze the hydrolytic deamination of 5'-substituted and 5'-protected 5'-deoxyedenosines, whereas limited or no activity is shown by adenosine deaminase (ADA) towards the same substrates.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Biotransformations; Deamination; Enzyme catalysis; Nucleosides
Elenco autori:
P. Ciuffreda, A. Loseto,L. Alessandrini, G. Terraneo, E. Santaniello
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