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Angiotensin-converting enzyme inhibition facilitates alveolar-capillary gas transfer and improves ventilation-perfusion coupling in patients with left ventricular dysfunction

Academic Article
Publication Date:
1999
Citation:
Angiotensin-converting enzyme inhibition facilitates alveolar-capillary gas transfer and improves ventilation-perfusion coupling in patients with left ventricular dysfunction / M. Guazzi, G. Melzi, G. C. Marenzi, P. Agostoni. - In: CLINICAL PHARMACOLOGY & THERAPEUTICS. - ISSN 0009-9236. - 65:3(1999 Mar), pp. 319-27-327.
abstract:
The backward effects of left ventricular dysfunction include alterations in alveolar-capillary gas transfer and ventilation-perfusion coupling. Because the angiotensin-converting enzyme (ACE) is highly concentrated in the vascular endothelium of the lungs, we examined whether ACE inhibitors may influence the pulmonary function in patients with congestive heart failure.
IRIS type:
01 - Articolo su periodico
Keywords:
Respiratory Function Tests; Heart Failure; Humans; Exercise; Capillaries; Cardiomyopathies; Matched-Pair Analysis; Exercise Test; Oxygen; Enalapril; Ventilation-Perfusion Ratio; Adult; Treatment Outcome; Case-Control Studies; Ventricular Dysfunction, Left; Angiotensin-Converting Enzyme Inhibitors; Middle Aged; Time Factors; Pulmonary Alveoli; Female; Male; Carbon Dioxide
List of contributors:
M. Guazzi, G. Melzi, G. C. Marenzi, P. Agostoni
Authors of the University:
AGOSTONI PIERGIUSEPPE ( author )
GUAZZI MARCO ( author )
Link to information sheet:
https://air.unimi.it/handle/2434/186838
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Settore MED/11 - Malattie dell'Apparato Cardiovascolare
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