A novel approach to the synthesis of precursors of tricyclic beta-lactam antibiotics

Articolo
Data di Pubblicazione:
1999
Citazione:
A novel approach to the synthesis of precursors of tricyclic beta-lactam antibiotics / R. Annunziata, M. Benaglia, M. Cinquini, F. Cozzi, L. Poletti, L. Raimondi, A. Perboni. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 1999:11(1999), pp. 3067-3072. [10.1002/(sici)1099-0690(199911)1999:11<3067::aid-ejoc3067>3.0.co;2-k]
Abstract:
The stereoselective synthesis of two precursors of tricyclic beta-lactam antibiotics (trinems) has been attempted by a novel approach that involves a highly stereoselective azetidinone ring-forming reaction followed by the reduction of a functionalized aromatic substituent at C-4 of the beta-lactam nucleus.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
thioester; enolate; imine; lactams; asymmetric synthesis
Elenco autori:
R. Annunziata, M. Benaglia, M. Cinquini, F. Cozzi, L. Poletti, L. Raimondi, A. Perboni
Autori di Ateneo:
BENAGLIA MAURIZIO ( autore )
RAIMONDI LAURA MARIA ( autore )
Link alla scheda completa:
https://air.unimi.it/handle/2434/181636

Aree Di Ricerca

Settori


Settore CHIM/06 - Chimica Organica