EMG del diaframma costale e crurale nel maiale neonato

The EMG of costal and crural diaphragm has been evaluated in 6 anaesthetized (Thiopentale mg 15/kg i.v.) and tracheostomized newborn pigs, 3-5 days old. The EMG has been evaluated in control condition, during resistive load and during PGF2alpha bronchoconstriction (mg 0.150-0.200/kg i.v.). Results evidenced that resistive load and bronchoconstriction cause an increase in Pdi and in EMG of costal and crural diaphragm. For a similar change in Pdi the costal and crural diaphragm activity is greater during PGF2alpha bronchoconstriction. The results evidence a central PGF2alpha activity on respiratory centers.