Lipase-catalyzed preparation of corticosteroid 17alpha-esters endowed with antiandrogenic activity
Articolo
Data di Pubblicazione:
2008
Citazione:
Lipase-catalyzed preparation of corticosteroid 17alpha-esters endowed with antiandrogenic activity / P. Ferraboschi, M. De Mieri, L. Ragonesi. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 49:31(2008 Jul 28), pp. 4610-4612.
Abstract:
Several 17alpha-monoesters of cortexolone and its delta 9-derivative are endowed with antiandrogenic activity. Their synthesis can be accomplished by means of a lipase-catalyzed chemoselective alcoholysis of the corresponding 17alpha,21-diesters.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Lipase ; corticosteroid ; chemoselective alcoholysis ; antiandrogen
Elenco autori:
P. Ferraboschi, M. De Mieri, L. Ragonesi
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