Data di Pubblicazione:
2011
Citazione:
Opto-electronic plethysmographic study of the chest wall after lung transplantation / M. Laviola, E. Privitera, M. Nosotti, A. Aliverti, L. Santambrogio, D. Tosi, L. Rosso. ((Intervento presentato al convegno ERS Annual Congress 2011 tenutosi a Amterdam nel 2011.
Abstract:
Opto‐eletronic plethysmographic study of the chest wall after lung
transplantation
Background: Lung transplantation is the established surgical therapy for
pulmonary end‐stage
disease.
Aims: Even though the pulmonary function after lung transplantation is well
studied, the chest volume changes remain uninvestigated. The aim of the
present study was to examine such changes by the optoelectronic
plethysmography (OEP), a non invasive technology.
Methods: Seven patients with end‐stage pulmonary disease were studied before
and after lung
transplantation by OEP during quiet and forced breathing. Standard pulmonary
function tests were also obtained. Three patients with pulmonary fibrosis had
single lung transplantation and four patients with cystic fibrosis had bilateral.
Result: The functional tests demonstrated increasing in pulmonary function (e.g.
FEV1 % from 44 ± 15 to 83 ± 6). After bilateral transplantation, the OEP revealed
a volume rearrangement: a decrease was noted in functional residual capacity
(FRC: ‐2.14 ± 1.3L), in vital capacity (‐ 1.1 ± 1.1L), in total lung capacity (– 2.59 ±
1.6L). The chest wall volume reduction was different in the upper thorax, lower
thorax and abdominal compartment (e.g. FRC: ‐0.68L, ‐0.13L ‐ 1.59L
respectively). After single lung transplantation the pattern was similar but less
evident.
Conclusions: This first, preliminary, study of the chest wall volume changes
reveals a rearrangement of such volumes after single or double lung
transplantation. Facing the dramatic improvement in spirometric value, OEP
recorded a decrease in volume parameters; such decreases were
inhomogeneous through the body compartments privileging the abdomen.
Further studies are needed to better understand the value of these findings and
their clinical impact.
Tipologia IRIS:
14 - Intervento a convegno non pubblicato
Elenco autori:
M. Laviola, E. Privitera, M. Nosotti, A. Aliverti, L. Santambrogio, D. Tosi, L. Rosso
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