Data di Pubblicazione:
2007
Citazione:
Antioxidant metabolism of Xenopus laevis embryos during the first days of development / A.M. Rizzo, L. Adorni, G. Montorfano, F. Rossi, B. Berra. - In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART B, BIOCHEMISTRY & MOLECULAR BIOLOGY. - ISSN 1096-4959. - 146:1(2007 Jan), pp. 94-100.
Abstract:
Reactive oxygen species (ROS) are formed and degraded in all aerobic organisms, but their role during embryonic development has not yet
been well established. In this paper, we report the activities of various enzymes involved in antioxidant metabolism during the first 7 days of
embryonic development of Xenopus laevis embryos. During the first two days of development, embryo antioxidant metabolism is based on
catalase and superoxide dismutase activities. Later, the glutathione system is activated, and the activity of all the enzymes involved increases. The
results presented in this study, together with previously reported data, support the hypothesis that antioxidant defences may include enzymes that
are genetically regulated, while the other systems that appear to be environmentally modulated become relevant later in development, probably to
protect embryos from environmental and toxic factors
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Embryonic development; Free radicals; Glutathione metabolism; Oxidative stress; Reactive oxygen species; Superoxide; TBARS; Xenopus laevis
Elenco autori:
A.M. Rizzo, L. Adorni, G. Montorfano, F. Rossi, B. Berra
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