Unveiling the multilevel impact of four water-soluble polymers on Daphnia magna: from proteome to behaviour (a case study)
Articolo
Data di Pubblicazione:
2024
Citazione:
Unveiling the multilevel impact of four water-soluble polymers on Daphnia magna: from proteome to behaviour (a case study) / L. Nigro, S. Magni, M.A. Ortenzi, S. Gazzotti, C. Della Torre, S.G. Signorini, R. Sbarberi, A. Binelli. - In: JOURNAL OF HAZARDOUS MATERIALS. - ISSN 0304-3894. - 469:(2024 May 05), pp. 134000.1-134000.18. [10.1016/j.jhazmat.2024.134000]
Abstract:
The ubiquitous presence of water-soluble polymers (WSPs) in freshwater environments raises concerns regarding
potential threats to aquatic organisms. This study investigated, for the first time, the effects of widely used WSPs
-polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), polyacrylic acid (PAA), and polyethylene glycol (PEG)-
using a multi-level approach in the freshwater biological model Daphnia magna. This integrated assessment
employed a suite of biomarkers, evaluation of swimming behaviour, and proteomic analysis to investigate the
effects of three environmentally relevant concentrations (0.001, 0.5, and 1 mg/L) of the tested WSPs from
molecular to organismal levels, assessing both acute and chronic effects. Our findings reveal that exposure to
different WSPs induces specific responses at each biological level, with PEG being the only WSP inducing lethal
effects at 0.5 mg/L. At the physiological level, although all WSPs impacted both swimming performance and
heart rate of D. magna specimens, PAA exhibited the greatest effects on the measured behavioural parameters.
Furthermore, proteomic analyses demonstrated altered protein profiles following exposure to all WSPs, with PVA
emerging as the most effective.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Synthetic polymers; Freshwaters; Chronic toxicity; Ecotoxicology; Ecology
Elenco autori:
L. Nigro, S. Magni, M.A. Ortenzi, S. Gazzotti, C. Della Torre, S.G. Signorini, R. Sbarberi, A. Binelli
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