2D TR-NOESY Experiments Interrogate and Rank Ligand-Receptor Interactions in Living Human Cancer Cells
Articolo
Data di Pubblicazione:
2010
Citazione:
2D TR-NOESY Experiments Interrogate and Rank Ligand-Receptor Interactions in Living Human Cancer Cells / S. Mari, C. Invernizzi, A. Spitaleri, L. Alberici, M. Ghitti, C. Bordignon, C. Traversari, G. Rizzardi, G. Musco. - In: ANGEWANDTE CHEMIE. - ISSN 0044-8249. - 122:6(2010), pp. 1089-1092. [10.1002/ange.200905941]
Abstract:
(Figure Presented) Cell mates: Various ligand-receptor interactions in different human cancer cell lines were probed directly by two-dimensional transferred-NOE spectroscopy (see picture) to prove recognition specificity and determine an affinity ranking of several ligands.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Drug design; Integrins; Nmr spectroscopy; Protein-ligand interactions
Elenco autori:
S. Mari, C. Invernizzi, A. Spitaleri, L. Alberici, M. Ghitti, C. Bordignon, C. Traversari, G. Rizzardi, G. Musco
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