Atovaquone-statine "Double-Drugs" with high antiplasmodial activity

Combining chemicals. Malaria is one of the most widespread parasitic infections in the world, however, the unavailability of a vaccine and the spread and intensification of drug resistance over the past 15-20 years have led to a dramatic decline in the efficacy of the most affordable antimalarial drugs. Herein, the development of "double-drugs" to tackle inhibition of P. falciparum growth is discussed. (Chemical Equation Presented).