Data di Pubblicazione:
2002
Citazione:
Chemoselective oxidation of primary alcohols to aldehydes with Gluconobacter oxydans / R. Villa, A. Romano, R. Gandolfi, J.V. Sinisterra Gago, F. Molinari. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 43:34(2002), pp. 6059-6061.
Abstract:
The production of aliphatic and aromatic aldehydes by oxidation of primary alcohols was achieved with Gluconobacter oxydans DSM 2343. The biotransformation was optimised studying the oxidation of 2-phenyl-1-ethanol to 2-phenylacetaldehyde. A high molar conversion (95% chromatographic conversion, 83% of isolated yield) was obtained using cells grown on glycerol as the main carbon source and directly used in the cultural medium after 24 h at 28°C, pH 4.5 and 5 g L−1 substrate concentration. The conversion of structurally different primary alcohols was performed under these conditions allowing the chemoselective production of aldehydes, sometimes with very good yields.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Alcohol oxidation; Aldehyde production; Biotransformation; Flavour; Gluconobacter oxydans
Elenco autori:
R. Villa, A. Romano, R. Gandolfi, J.V. Sinisterra Gago, F. Molinari
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