A regioselective route to 5-substituted pyrazole- and pyrazoline-3-phosphonic acids and esters

Academic Article

Publication Date:

2007

Citation:

A regioselective route to 5-substituted pyrazole- and pyrazoline-3-phosphonic acids and esters / P. Conti, A. Pinto, L. Tamborini, V. Rizzo, C. De Micheli. - In: TETRAHEDRON. - ISSN 0040-4020. - 63:25(2007 Jun 18), pp. 5554-5560. [10.1016/j.tet.2007.04.027]

abstract:

The regioselective synthesis of 5-substituted-3-dimethoxyphosphono-pyrazoles and -2-pyrazolines has been accomplished through the 1,3-dipolar cycloaddition of a suitable nitrile imine to monosubstituted alkynes and alkenes. Examples of hydrolysis of the heterocyclic phosphonic esters to the corresponding acids are described.

IRIS type:

01 - Articolo su periodico

List of contributors:

P. Conti, A. Pinto, L. Tamborini, V. Rizzo, C. De Micheli

Authors of the University:

CONTI PAOLA ( author )

PINTO ANDREA ( author )

TAMBORINI LUCIA ( author )

Link to information sheet:

https://air.unimi.it/handle/2434/35275

Research Areas

Concepts

Old Academic field (valid till 24/06/2024)

Settore CHIM/08 - Chimica Farmaceutica

A regioselective route to 5-substituted pyrazole- and pyrazoline-3-phosphonic acids and esters

P. Conti, A. Pinto, L. Tamborini, V. Rizzo, C. De Micheli

Research Areas

Concepts